Zixuan (Eleanor) Zhang

Zixuan (Eleanor) Zhang

PhD candidate in Biostatistics at USC

Publications

You can also find my articles on my Google Scholar profile.

Inferring causal cell types of human diseases and risk variants from candidate regulatory elements

Published in medRxiv (preprint), 2024

We proposed methods to leverage cell-type-specific CREs to fine-map causal cell types for a trait and for its candidate causal variants.

Recommended citation: Kim, A., Zhang, Z., Legros, C., Lu, Z., de Smith, A., Moore, J.E., Mancuso, N., and Gazal, S. (2024). Inferring causal cell types of human diseases and risk variants from candidate regulatory elements. medRxiv.
Download Paper

A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics

Published in American Journal of Human Genetics, 2023

We proposed a scalable factor analysis model to identify and characterize pleiotropic components using biobank GWAS summary data.

Recommended citation: Zhang, Z., Jung, J., Kim, A., Suboc, N., Gazal, S., and Mancuso, N. (2023). A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics. Am. J. Hum. Genet. 110, 1863–1874.
Download Paper